折损率公式职业卫生生物监测方法检出限和定量限计算方法探讨

2020年10月4日发(作者：李厚霖)

职业卫生生物监测方法检出限和定量限计算方法探讨
崔师伟;闫慧芳


【期刊名称】《中华劳动卫生职业病杂志》

【年(卷),期】2018(036)007

【摘要】目的 探讨职业卫生生物监测方法检出限和定量限的计算方法.方法 通
过IUPAC、NIOSH、OSHA 三种不同方法分别计算苯乙醛酸和苯乙醇酸的检
出限和定量限.结果 采用IUPAC、NIOSH、O SHA三种不同方法计算的苯乙醛
酸和苯乙醇酸的检出限和定量限各不相同.结论 计算职业卫生生物监 测方法检出
限和定量限时,为保证检出限附近的检出率及定量限附近有75％以上的回收率
应采 用标准曲线法,通过一系列浓度加标的方式来计算检出限和定量
限.%Objective To discuss calculation method of detection limit and
quantitative limit of occupational health biological s
The detection limit and the quantitative limit of phenyl glyoxylic acid
and Mandelic acid were calculated by using three different methods of
IUPAC,NIOSH and OSHA s The IUPAC,NIOSH and
OSHA methods were used to calculate the detection limit and the
quantitative limit of the phenyl glyoxylic acid and Mandelic acid,and the
results are sion To calculate the detection limit and
quantitative limit of occupational health biological monitoring
methods,the standard curve method is adopted to ensure that the rate
of detection in the vicinity of detection limit and more than 75％ of the
quantitative limits are used.